INFEKSI MENULAR SEKSUAL DAN RIWAYAT KONTRASEPSI HORMONAL SEBAGAI FAKTOR RESIKO LESI PRA-KANKER LEHER RAHIM

weni tri purnani(1*), siswi wulandari(2), Anita Nuril Fadila(3), Nuridani nuridani(4),

(1) Universitas Kadiri
(2) Universitas Kadiri
(3) Universitas Kadiri
(4) Universitas Kadiri
(*) Corresponding Author

Abstract


Background and purpose: Currently examination with IVA and pap smear for pre-cervical lesion screening has been carried out in East Java Province. This study aims to find out hormonal contraceptives and the history of STIs as risk factors for pre-cervical cancer lesions.

Method: The research design is a case-control with a sample of 76 PUS women who were positively diagnosed with pre-cancerous lesions with IVA examinations and confirmation of pap smear examinations at two health centers in Kediri City from February to July 2020. Control as many as 76 PUS women were selected from those who were negative in the same period. Case samples and controls are selected consecutively. Data on risk factors is collected through interviews using questionnaires. Data analysis is done by logistic regression method to get adjusted odd ratio of each risk factor.

Result: Multivariate analysis showed that hormonal contraceptive use (>5 years and <5 years) increased the risk of pre-cervical lesions compared to those who did not use hormonal contraceptives respectively with OR=10.7 (95%CI:1.04-108.17) and OR=3.0 (95% CI: 1.16-7.84). A history of STIs also increases the risk of pre-cancerous cervical lesions by OR=9.7 (95%CI: 3.83-24.18).

Conclusion: The use of hormonal contraceptives and a history of sexually transmitted infections increases the risk of pre-cervical lesions.

Keywords


pre-cancerous cervical lesions, hormonal contraceptives, history of sexually transmitted infections

Full Text:

PDF

References


Andrijono. 2013. Sinopsis Kanker Ginekologi. Jakarta: Divisi Onkologi Departemen Obstetri Ginekologi, Fakultas Kedokteran Universitas Indonesia.

Andrijono. 2019. Kanker Serviks. Jakarta: Divisi Onkologi Departemen Obstetri Ginekologi Fakultas Kedokteran Universitas Indonesia

BKKBN. 2015. Keluarga Berencana dan Kontrasepsi. Cetakan ke5. Jakarta: Pustaka Sinar Harapan

Carol, Jones, et al. 2015. Risk Factors for Insitu Cervical Cancer: Results from a Case-Control Study Cancerres. AACR Journals.org. Available from URL: http:// cancerres.Aacr journals.Org site/misc/ terms.xhtml.

Delia, W. 2010. Pembunuh Ganas itu Bernama Kanker Servik. Yogyakarta: Kejora.

Departemen Kesehatan RI. 2018. Skrining Kanker Leher Rahim Dengan Metode IVA. Jakarta: Depkes RI

Dinas Kesehatan Kota Kediri. 2019. Profil Kesehatan Kota Kediri Tahun 2018. Kediri: Kesehatan Kota Kediri.

Dinas Kesehatan Provinsi jawa Timur. Profil Kesehatan Provinsi Jawa Timur Tahun 2018. Jawa Timur: Dinas Kesehatan Provinsi Jawa Timur

Dr. Taufan Nugroho, dkk. (2014 ). Buku Ajar Asuhan Kebidanan 1 Kehamilan. Yogyakarta: Nuhamedika.

Harahap. 2016. Neoplasia Intraepitel pada Kanker Serviks (NIS), Pendekatan Ilmiah Pencegahan Kanker Leher Rahim. Jakarta: UI Press.

Kementerian Kesehatan Republik Indonesia. 2017. Profil Kesehatan Indonesia. Jakarta. Kementerian Kesehatan Republik Indonesia. 2014-2016.

Kementerian Kesehatan RI. 2015. Kesehatan dalam Kerangka Sistainable Development Goals (SDG'S). Jakarta: Kementerian Kesehatan RI; 2015.

Kementerian Kesehatan RI. 2016. INFODATIN Pusat Data dan Informasi Kementerian Kesehatan RI Situasi Kejadian Kanker Serviks. Jakarta Selatan.

Kharsany, Hoosen. 2012.The Association Between Sexually Transmitted Pathogens and Cervical Intraepithelial Neoplasia in a Developing Community. Genitourin Med 2012;69:35

Manuaba, Ida Bagus Gde. 2015. Pengantar Kuliah Obtetri. EGC. Jakarta.

Mastutik, G., dkk., 2015. Skrining Kanker Serviks dengan Pemeriksaan Pap Smear di Puskesmas Tanah Kali Kedinding Surabaya dan Rumah Sakit Mawadah Mojokerto. Majalah Obstetri & Ginekologi; 23 (2) : 54−60.

Melva. 2018. Faktor-Faktor Yang Mempengaruhi Kejadian Kanker Leher Rahim Di RSUP Adam Malik (tesis). Sumatera Utara: Universitas Sumatera Utara

Proverawati Atikah dkk. 2010. Panduan Memilih Kontrasepsi. Yogyakarta: Numed

Rasjidi. 2008. Manual Prakanker Serviks. Jakarta: Sagung Seto

Rusmana. 2019. Aspek Onkologi Human Papillomavirus. Fakultas Kedokteran, Universitas Kristen Maranatha, JKM..

Sani, Ridwan Abdullah. 2016. Penilaian Autentik. Jakarta: PT. Bumi Aksara

Suriani, 2013. Faktor Risiko Lesi Prakanker Leher Rahim pada PUS di Kecamatan Payangan Gianyar. Tesis. Denpasar: Universitas Udayana.

Suwiyoga, IK. 2010. Beberapa Masalah Pap Smear Sebagai Alat Diagnosis Dini Kanker Serviks Di Indonesia. Jurnal Studi Jender Srikandi. Available from URL: http:ojs.unud.ac.id/index.php/srikandi/article/view/275

Suwiyoga, IK. 2010. Beberapa Masalah Pap Smear Sebagai Alat Diagnosis Dini Kanker Serviks Di Indonesia. Jurnal Studi Jender Srikandi. 2010. Available from URL: http:ojs.unud.ac.id/index.php/srikandi/article/view/2755.

Triwahuningsih. 2013. Faktor Risiko Yang Berhubungan Dengan Kejadian Lesi Prakanker Leher Rahim Dengan Metode IVA di Puskesmas Jatinegara (tesi). Jakarta: Universitas Esa Unggul.

WHO/ICO. 2013. Comprehensive Cervical Cancer Prevention and Control a Healthier Future for Girls and Women: Summary Report update 2013.

Yustitia, Riski Ratnashinta dan Mayura, I Gusti Putu Mayun. 2016. Prevalensi Pasien Iva Positif Melalui Metode See And Treatdi Puskesmas Tabanan III Kabupaten Tabanan Periode Bulan Januari-Juni 2014. E-Jurnal Medika, Vol. 5 No.11, November, 2016




DOI: http://dx.doi.org/10.30737/jubitar.v2i1.1611

DOI (PDF): http://dx.doi.org/10.30737/jubitar.v2i1.1611.g1473

Article Metrics

Abstract view : 229 times
PDF - 153 times

Refbacks

  • There are currently no refbacks.


Jurnal Bidan Pintar by :

 

View My Statsvar sc_project=12346255; var sc_invisible=0; var sc_security="945f0d96"; var sc_https=1; var scJsHost = "https://"; document.write(""); View My Stats// ]]>

Flag Counter